- Granit, Ragnar Arthur (Swedish physiologist)
Ragnar Arthur Granit was a Finnish-born Swedish physiologist who was a corecipient (with George Wald and Haldan Hartline) of the 1967 Nobel Prize for Physiology or Medicine for his analysis of the internal electrical changes that take place when the eye is exposed to light. Granit received an M.D.
- granita (food)
sherbet: Water ice, called in French sorbet and in Italian granita, is similar to sherbet but contains no dairy ingredients.
- granite (mineral)
granite, coarse- or medium-grained intrusive igneous rock that is rich in quartz and feldspar; it is the most common plutonic rock of the Earth’s crust, forming by the cooling of magma (silicate melt) at depth. Because of its use as paving block and as a building stone, the quarrying of granite
- Granite City (Illinois, United States)
Granite City, city, Madison county, southwestern Illinois, U.S. Situated on the Mississippi River just northeast of St. Louis, Missouri, it lies within that city’s metropolitan area. Granite City was first settled in the early 19th century as a farming community and known as Six Mile Prairie,
- Granite Creek (Queensland, Australia)
Mareeba, town, northeastern Queensland, Australia, on the Barron River, 40 miles (65 km) west of the port of Cairns on the Coral Sea. It was the earliest European settlement on the Atherton Plateau; at its founding it was called Granite Creek and served as a stop for miners on their way to
- Granite Creek Desert (region, Nevada, United States)
Black Rock Desert, arid region of lava beds and alkali flats composing part of the Basin and Range Province and lying in Humboldt and Pershing counties of northwestern Nevada, U.S. With an area of about 1,000 square miles (2,600 square km), the desert is 70 miles (110 km) long and up to 20 miles
- granite moss (plant)
granite moss, any of the plants of the order Andreaeales of the subclass Andreaeidae, comprising a single family, Andreaeaceae, which includes the genus Andreaea, with fewer than 100 species, including A. fuegiana, which formerly made up the separate genus of Neuroloma. The reddish brown or
- granite night lizard (reptile)
night lizard: A close relative, the granite night lizard (X. henshawi), lives in crevices, where it moves about during the day.
- Granite Peak (mountain, Montana, United States)
Granite Peak, peak in the Beartooth Range, Montana, U.S., the highest point (12,799 feet [3,901 metres]) in the state. Granite Peak is situated northeast of Yellowstone National Park and about 10 miles (16 km) north of the Montana-Wyoming border in the Absaroka-Beartooth Wilderness, an area of high
- Granite Railway (American railway)
Granite Railway, first chartered railroad in the United States (March 4, 1826). It was designed and built by Gridley Bryant, an engineer, and began operations on Oct. 7, 1826, running three miles from Quincy, Mass., to the Neponset River. The wooden rails were plated with iron and were laid 5 feet
- Granite State, The (state, United States)
New Hampshire, constituent state of the United States of America. One of the 13 original U.S. states, it is located in New England at the extreme northeastern corner of the country. It is bounded to the north by the Canadian province of Quebec, to the east by Maine and a 16-mile (25-km) stretch of
- graniteware (pottery)
Granite City: …base for the production of graniteware (enameled ironware), and the city was founded four years later. Although graniteware gave the city its name, the product is no longer manufactured there. Steel founding began in Granite City in 1894 and is the basis of the economy. The manufacture of automotive parts…
- granitic magma (geology)
igneous rock: Origin of magmas: Granitic, or rhyolitic, magmas and andesitic magmas are generated at convergent plate boundaries where the oceanic lithosphere (the outer layer of Earth composed of the crust and upper mantle) is subducted so that its edge is positioned below the edge of the continental plate or…
- granitization (geology)
granitization, formation of granite or closely related rocks by metamorphic processes, as opposed to igneous processes in which such rocks form from a melt, or magma, of granitic composition. In granitization, sediments are transformed in their solid state or in a partially molten state. The
- Granja De San Ildefonso, La (factory, Spain)
La Granja De San Ildefonso, Spanish royal glass factory established in 1728 near the summer palace of King Philip V in San Ildefonso. The glassworkers were initially foreigners; the main stylistic influence was, as in earlier Spanish glass, that of Venice. Glass from La Granja carried on many of
- Granja, La (palace, San Ildefonso, Spain)
San Ildefonso: …planned to build a summer palace there that would rival those at Versailles, France, and Parma, Italy.
- Granjon, Robert (French printer)
typography: France: …departures in type design was Robert Granjon, who, in addition to fashioning some notable versions of Garamond types, also tried—with his type called Civilité—to create a fourth major typeface to be different from and stand alongside roman, italic, and Gothic. He envisioned it as a national type for the use…
- Granma (Cuban newspaper)
Granma, daily newspaper published in Havana, the official organ of the Central Committee of the Communist Party of Cuba. The paper takes its name from the yacht that carried Fidel Castro and others supporting his revolution from Mexico to Cuba in 1956. Granma was established in 1965 by the merger
- Granmont, Louis (French buccaneer)
Louis Granmont was one of the most celebrated of French buccaneers, a scourge of the Spanish settlements bounding the Caribbean. Granmont first distinguished himself in service in the French royal marines, but, having illegally gambled away a captured prize cargo in Hispaniola (Haiti), he dared not
- granny knot (mathematics)
knot theory: …the square knot and the granny knot (sixth-order knots) are products of two trefoils that are of the same or opposite chirality, or handedness. Knots that cannot be so resolved are called prime.
- granodiorite (rock)
granodiorite, medium- to coarse-grained rock that is among the most abundant intrusive igneous rocks. It contains quartz and is distinguished from granite by its having more plagioclase feldspar than orthoclase feldspar; its other mineral constituents include hornblende, biotite, and augite. The
- Granollers (Spain)
Granollers, city, Barcelona provincia (province), in the comunidad autónoma (autonomous community) of Catalonia, northeastern Spain. It has many fine medieval houses and the 12th-century Gothic church of San Esteban. Called Granullaria (from the Latin word for grain) by the Romans because of its
- granophyre (rock)
granophyre, fine-grained igneous rock that is characterized by a porphyritic texture, having large crystals (phenocrysts) that rest in a nonglassy, finely crystalline matrix (groundmass). Granophyre is similar to granite, except for its fine texture and smaller grain size; those granophyres that
- Granovetter, Mark (economic sociologist)
economic sociology: Contemporary economic sociology: …coined by the economic sociologist Mark Granovetter, who emphasized the embeddedness of economic action in concrete social relations. Granovetter contended that institutions are actually congealed social networks, and, because economic action takes place within these networks, social scientists must consider interpersonal relationships when studying the economy. Markets themselves were studied…
- Grant (county, New Mexico, United States)
Grant, county, southwestern New Mexico, U.S., a scenic region bordered on the west by Arizona. The Continental Divide crosses the county. The wide northern section of Grant county lies for the most part in the Datil section of the Colorado Plateaus, an area including the Mogollon, Mule, Mimbres,
- Grant Island (island, Australia)
Phillip Island, island astride the entrance to Western Port (bay) on the south coast of Victoria, Australia, southeast of Melbourne. About 14 miles (23 km) long and 6 miles (10 km) at its widest, the island occupies 40 square miles (100 square km) and rises to 360 feet (110 metres). Visited in 1798
- Grant Park (park, Chicago, Illinois, United States)
Chicago Marathon: …marathon’s route begins downtown in Grant Park, winds through the Loop, and runs through the North Side before returning downtown. It then circles through the city’s West and South sides before ending back in Grant Park. Khalid Khannouchi (of Morocco and later the U.S.) won the most Chicago Marathons with…
- Grant Park Municipal Stadium (stadium, Chicago, Illinois, United States)
Soldier Field, stadium in Chicago that was built in 1924 and is one of the oldest arenas in the NFL, home to the city’s professional gridiron football team, the Bears, since 1971. In 1919 the South Park Commission (later reorganized as the Chicago Park District) held a design competition for what
- Grant’s gazelle (mammal)
gazelle: …three largest species—the dama gazelle, Grant’s gazelle, and Soemmering’s gazelle—are placed in the genus Nanger (formerly considered a subgenus), and three of the smaller species—Thomson’s gazelle, the red-fronted gazelle, and the Mongalla gazelle—have become the genus Eudorcas. The Gazella genus as
- Grant’s golden mole (mammal)
golden mole: Natural history: Grant’s golden mole (Eremitalpa granti) of southern Africa is a sand-dune inhabitant. It does not live in burrows but travels at night on the dune surface or just below, employing its front limbs and muzzle to “swim” through the sand. During the day it buries…
- Grant’s Tomb (monument, New York City, New York, United States)
General Grant National Memorial, mausoleum of U.S. President Ulysses S. Grant in New York City, standing on a bluff overlooking the Hudson River. It was designed by John H. Duncan. The monument, 150 feet (46 m) high in gray granite, was erected at a cost of $600,000 raised by public contributions.
- Grant’s zebra (mammal)
zebra: quagga boehmi (Grant’s zebra), E. quagga chapmani (Chapman’s zebra), E. quagga burchellii (Burchell’s zebra), and E. quagga quagga (quagga, which is extinct). The mountain zebra is made up of two subspecies: E. zebra hartmannae (Hartmann’s mountain zebra) and E. zebra zebra (
- Grant, Alexander (British military officer)
Banjul: …British Colonial Office ordered Captain Alexander Grant to establish a military post on the river to suppress the slave trade and to serve as a trade outlet for merchants ejected from Senegal, which had been restored to France. Grant chose Banjul Island (ceded by the chief of Kombo) as the…
- Grant, Arvid (American engineer)
bridge: U.S. designs: Designed by Arvid Grant in collaboration with the German firm of Leonhardt and Andra, its cost was not significantly different from those of other proposals with more conventional designs. The same designers produced the East End Bridge across the Ohio River between Proctorville, Ohio, and Huntington, West…
- Grant, Bernard Alexander Montgomery (British politician)
Bernie Grant was a British politician who, with Paul Boateng and Diane Abbott, was one of the first persons of African descent to win election to the House of Commons. The son of educators, he attended St. Stanislaus College, one of the finest schools in British Guiana. In the early 1960s he moved
- Grant, Bernie (British politician)
Bernie Grant was a British politician who, with Paul Boateng and Diane Abbott, was one of the first persons of African descent to win election to the House of Commons. The son of educators, he attended St. Stanislaus College, one of the finest schools in British Guiana. In the early 1960s he moved
- Grant, Bud (American football coach)
Minnesota Vikings: …the hiring of head coach Bud Grant in 1967. Grant, a future member of the Hall of Fame, guided the Vikings to all four of their Super Bowl appearances over the course of his career. His Vikings teams of the 1970s featured a tenacious defensive line known as the “Purple…
- Grant, Cary (British-born American actor)
Cary Grant was a British-born American film actor whose good looks, debonair style, and flair for romantic comedy made him one of Hollywood’s most popular and enduring stars. To escape poverty and a fractious family, Archie Leach ran away from home at age 13 to perform as a juggler with the Bob
- Grant, Charlie (American baseball player)
John McGraw: …contract of African American player Charlie Grant from the Negro league Columbia Giants. Because of the segregation that existed in baseball, McGraw tried to pass Grant off as a Cherokee Indian. The ruse was unsuccessful, and the colour bar would not be breached until Branch Rickey signed Jackie Robinson in…
- Grant, Duncan (British painter)
Duncan Grant was an innovative British Post-Impressionist painter and designer. He was one of the first English artists to assimilate the influence of Paul Cézanne and the Fauves. The son of a military officer, Grant spent several years of his youth in India and was educated at St. Paul’s School,
- Grant, Elizabeth Woolridge (American singer-songwriter)
Lana Del Rey is an American singer-songwriter known for pairing glamorously morose musical themes with classic Americana and a nostalgic, cinematic visual style. Del Rey’s songs typically focus on relatable, melancholic experiences wrapped in a cultural pastiche of Hollywood’s golden era. The
- Grant, Frank (American baseball player)
baseball: Segregation: …Stovey, pitcher Robert Higgins, and Frank Grant, a second baseman who was probably the best Black player of the 19th century, were on rosters of clubs in the International League, one rung below the majors. At least 15 other Black players were in lesser professional leagues. Although they suffered harassment…
- Grant, George (Canadian philosopher)
George Grant was a Canadian philosopher who achieved national renown with his pessimistic 97-page book, Lament for a Nation: The Defeat of Canadian Nationalism (1965). Grant was educated at Queen’s University, Kingston, Ontario, and in England at the University of Oxford, where he was a Rhodes
- Grant, Harry J. (American editor)
Milwaukee Journal Sentinel: Harry J. Grant had become editor of The Milwaukee Journal in 1919, and after the Niemans’ deaths he organized a plan whereby employees could buy stock in the company; more than 700 did so, and the employees eventually acquired control of the paper. In 1962…
- Grant, Hiram Ulysses (president of United States)
Ulysses S. Grant was a U.S. general, commander of the Union armies during the late years (1864–65) of the American Civil War, and the 18th president of the United States (1869–77). Grant was the son of Jesse Root Grant, a tanner, and Hannah Simpson, and he grew up in Georgetown, Ohio. Detesting the
- Grant, Hugh (British actor)
Hugh Grant is a British actor best known for his leading roles as the endearing and funny love interest in romantic comedies. It was not until Grant’s senior year at the University of Oxford, where he was studying English literature, that he became involved in acting. He appeared in a student film,
- Grant, Hugh John Mungo (British actor)
Hugh Grant is a British actor best known for his leading roles as the endearing and funny love interest in romantic comedies. It was not until Grant’s senior year at the University of Oxford, where he was studying English literature, that he became involved in acting. He appeared in a student film,
- Grant, James Augustus (British explorer)
James Augustus Grant was a Scottish soldier and explorer who accompanied John Hanning Speke in the search for and discovery of the source of the Nile River. Commissioned in the British army in 1846, Grant saw action in India in the Sikh Wars and the Indian Mutiny of 1857. When Speke started his
- Grant, Julia (American first lady)
Julia Grant was an American first lady (1869–77), the wife of Ulysses S. Grant, 18th president of the United States and commander of the Union armies during the last years of the American Civil War. A popular first lady, she was noted for her informal manner and opulent entertaining. Daughter of
- Grant, Kathryn (American actress)
Anatomy of a Murder: Cast:
- Grant, Lee (American actress and director)
- Grant, Madison (American lawyer)
eugenics: Eugenics organizations and legislation: …group, the New York lawyer Madison Grant, aroused considerable pro-eugenic interest through his best-selling book The Passing of the Great Race (1916). Beginning in 1920, a series of congressional hearings was held to identify problems that immigrants were causing the United States. As the country’s “eugenics expert,” Harry Laughlin provided…
- Grant, Mary Jane (Jamaican nurse)
Mary Seacole was a Jamaican businesswoman who provided sustenance and care for British soldiers at the battlefront during the Crimean War. Her father was a Scottish soldier, and her mother was a free black Jamaican woman and “doctress” skilled in traditional medicine who provided care for invalids
- Grant, Micki (American musician and songwriter)
Vinnette Carroll: …with music and lyrics by Micki Grant, opened on Broadway in 1972 with Carroll as director and was nominated for four Tony Awards. Her adaptation of The Gospel According to Matthew, Your Arms Too Short to Box with God (also in collaboration with Grant), opened on Broadway in 1976 and…
- Grant, Richard (archbishop of Canterbury)
Richard le Grant was the 45th archbishop of Canterbury (1229–31), who asserted the independence of the clergy and of his see from royal control. Richard was the chancellor of Lincoln Cathedral (1221–29), Lincolnshire. He was then appointed archbishop by Pope Gregory IX at the request of King Henry
- Grant, Sir John Peter (British colonial governor)
Jamaica: The crown colony: Its newly appointed governor, Sir John Peter Grant, wielded the only real executive or legislative power. He completely reorganized the colony, establishing a police force, reformed judicial system, medical service, public works department, and government savings bank. He also appointed local magistrates, improved the schools, and irrigated the fertile…
- Grant, Ulysses S. (president of United States)
Ulysses S. Grant was a U.S. general, commander of the Union armies during the late years (1864–65) of the American Civil War, and the 18th president of the United States (1869–77). Grant was the son of Jesse Root Grant, a tanner, and Hannah Simpson, and he grew up in Georgetown, Ohio. Detesting the
- Grant, Zilpah Polly (American educator)
Zilpah Polly Grant was a 19th-century American educator who, through her teaching and administrative efforts, was instrumental in promoting advanced educational opportunities for women. Grant attended local schools and, to the extent her frail health allowed, worked to help her widowed mother keep
- Granth (Sikh sacred scripture)
Adi Granth, the sacred scripture of Sikhism, a religion of India. It is a collection of nearly 6,000 hymns of the Sikh Gurus (religious leaders) and various early and medieval saints of different religions and castes. The Adi Granth is the central object of worship in all gurdwaras (Sikh temples)
- Granth Sahib (Sikh sacred scripture)
Adi Granth, the sacred scripture of Sikhism, a religion of India. It is a collection of nearly 6,000 hymns of the Sikh Gurus (religious leaders) and various early and medieval saints of different religions and castes. The Adi Granth is the central object of worship in all gurdwaras (Sikh temples)
- Grantha alphabet
Grantha alphabet, writing system of southern India developed in the 5th century ad and still in use. The earliest inscriptions in Grantha, dating from the 5th–6th century ad, are on copper plates from the kingdom of the Pallavas (near modern Madras). The form of the alphabet used in these
- Grantha script
Grantha alphabet, writing system of southern India developed in the 5th century ad and still in use. The earliest inscriptions in Grantha, dating from the 5th–6th century ad, are on copper plates from the kingdom of the Pallavas (near modern Madras). The form of the alphabet used in these
- Grantham (England, United Kingdom)
Grantham, town, South Kesteven district, administrative and historic county of Lincolnshire, east-central England. It lies on the River Witham. Of Saxon origin, Grantham is mentioned in Domesday Book (1086), and its royal charter of incorporation was granted in 1463. In the Middle Ages Grantham
- granting judgment as a matter of law (law)
procedural law: Directed verdicts: When the party having the burden of proof of an issue has completed its presentation, the opposing side may ask the court to rule as a matter of law that the evidence presented does not provide sufficient proof for the party who presented…
- Granting of Independence to Colonial Countries and Peoples, Declaration on the (UN)
United Nations: Dependent areas: This resolution, called the Declaration on the Granting of Independence to Colonial Countries and Peoples, condemned “the subjection of peoples to alien subjugation, domination and exploitation” and declared that “immediate steps shall be taken…to transfer all powers” to the peoples in the colonies “without any conditions or reservations, in…
- Grants (New Mexico, United States)
Grants, city, seat (1981) of Cibola county, west-central New Mexico, U.S., on the San Jose River. The site of a skirmish between Navajo and Comanche Indians in the early 19th century, the town was established in 1881 when the Grant brothers, contractors building the Atchison, Topeka and Santa Fe
- Grants Pass (Oregon, United States)
Grants Pass, city, seat (1886) of Josephine county, southwestern Oregon, U.S., on the Rogue River, in the Klamath Mountains, 25 miles (40 km) northwest of Medford. A stage stop on the Sacramento-Portland overland route, it was named to commemorate Union General Ulysses S. Grant’s victory at
- granular cell layer (of epidermis)
human skin: Major layers: …by the granular layer, or stratum granulosum, with granules of keratohyalin contained in the cells. These small particles are of irregular shape and occur in random rows or lattices. The cells of the outer spinous and granular layers also contain much larger, lamellated bodies—the membrane-coating granules. They are most numerous…
- granular cell layer (of cerebellar cortex)
integument: Skin structure: …through a granular layer (stratum granulosum), in which they become laden with keratohyalin, a granular component of keratin. Finally the cells flatten, lose their nuclei, and form the stratum corneum. The dead cells at the skin surface are ultimately sloughed, or desquamated. In thick, glabrous skin lacking hair follicles,…
- granular cereal (food)
cereal processing: Granular cereals: Granular types are made by very different processes from the others. The first step is production of a stiff dough from wheat, malted barley flour, salt, dry yeast, and water. After mixing, fermentation proceeds for about five hours. The dough is then formed…
- granular enterochromaffin cell (anatomy)
human digestive system: Production and secretion of peptides: …a hormone produced by the granular gastrin (G) cells in the mucosa of the gastric antrum (the lower part of the stomach), is secreted into the blood.
- granular leukocyte (biology)
granulocyte, any of a group of white blood cells (leukocytes) that are characterized by the large number and chemical makeup of the granules occurring within the cytoplasm. Granulocytes are the most numerous of the white cells and are approximately 12–15 μm in diameter, making them larger than red
- granular pneumocyte (cell)
human respiratory system: The gas-exchange region: …more cuboidal cell type, the type II pneumocyte, covers the remaining surface. The type I cells form, together with the endothelial cells, the thin air–blood barrier for gas exchange; the type II cells are secretory cells. Type II pneumocytes produce a surface-tension-reducing material, the pulmonary surfactant, which spreads on the…
- granularity (igneous rock)
mineral: Crystal habit and crystal aggregation: …such aggregations are given here: granular, an intergrowth of mineral grains of approximately the same size; lamellar, flat, platelike individuals arranged in layers; bladed, elongated crystals flattened like a knife blade; fibrous, an aggregate of slender fibres, parallel or radiating; acicular, slender, needlelike crystals; radiating, individuals
- granulated filigree (art)
jewelry: Metalwork: …the shape of beads called granulated filigree.
- granulated tapioca (food)
tapioca: Granulated tapioca, marketed in various-sized grains and sometimes called “manioca,” is produced by grinding flake tapioca. When cooked, tapioca swells into a pale, translucent jelly.
- granulation (jewelry decoration)
granulation, in jewelry, type of decoration in which minute grains or tiny balls of gold are applied to a surface in geometric or linear patterns or massed to fill in parts of a decoration. First used as early as the 3rd millennium bc, it was known in western Asia and Egypt. The technique as
- granulation tissue (physiology)
inflammation: Healing and repair: …vascularized connective tissue is called granulation tissue. It derives its name from the small red granular areas that are seen in healing tissue (e.g., the skin beneath a scab). As repair progresses, new blood vessels establish blood circulation in the healing area, and fibroblasts produce collagen that imparts mechanical strength…
- granule (cytology)
bacteria: Cytoplasmic structures: …are numerous inclusion bodies, or granules, in the bacterial cytoplasm. These bodies are never enclosed by a membrane and serve as storage vessels. Glycogen, which is a polymer of glucose, is stored as a reserve of carbohydrate and energy. Volutin, or metachromatic granules, contains polymerized phosphate and represents a storage…
- granule (pharmacology)
pharmaceutical industry: Modified-release dosage forms: …by incorporating coated beads or granules into tablets or capsules. Drug is distributed onto or into the beads. Some of the granules are uncoated for immediate release while others receive varying coats of lipid, which delays release of the drug. Another variation of the coated bead approach is to granulate…
- granule ripple (geology)
sand dune: Sands: …features are generally known as granule ripples rather than dunes. Larger particles, such as small boulders, can be moved by the wind only on slippery surfaces (e.g., ice or wet saline mud) and never form into dunes.
- granulite (rock)
metamorphic rock: Metamorphic facies: …has resulted in the name granulite for a high-temperature metabasalt. A pelitic or calcareous rock will develop very different mineral assemblages from a metabasalt, yet the same facies names apply. Thus, one can refer to a greenschist facies pelitic schist, an amphibolite facies calcsilicate rock, or a granulite facies garnet…
- granulite facies (geology)
granulite facies, one of the major divisions of the mineral facies classification of metamorphic rocks, the rocks of which formed under the most intense temperature-pressure conditions usually found in regional metamorphism. At the upper limit of the facies, migmatite formation may occur.
- granulite–gneiss belt (geology)
Archean Eon: In granulite-gneiss belts the roots of many Andean-type active continental margins are exposed, the rocks being highly deformed and recrystallized during metamorphism in the deep crust. Common rocks are tonalites (a granitic-type rock rich in plagioclase feldspar) transformed into tonalitic gneisses, amphibolite dikes, and amphibolites derived from…
- Granullaria (Spain)
Granollers, city, Barcelona provincia (province), in the comunidad autónoma (autonomous community) of Catalonia, northeastern Spain. It has many fine medieval houses and the 12th-century Gothic church of San Esteban. Called Granullaria (from the Latin word for grain) by the Romans because of its
- granulocyte (biology)
granulocyte, any of a group of white blood cells (leukocytes) that are characterized by the large number and chemical makeup of the granules occurring within the cytoplasm. Granulocytes are the most numerous of the white cells and are approximately 12–15 μm in diameter, making them larger than red
- granulocyte colony-stimulating factor (biology)
therapeutics: Hematopoietic growth factors: Filgrastim (granulocyte colony-stimulating factor [G-CSF]) is used to stimulate the production of white blood cells, which prevents infection in patients whose white blood cell count has diminished because of the effects of anticancer drugs. G-CSF also mobilizes stem cells, prompting them to enter the peripheral…
- granulocyte-macrophage colony-stimulating factor (protein)
Alzheimer disease: Lifestyle factors and prevention: A protein known as GM-CSF (granulocyte-macrophage colony-stimulating factor), which is present in arthritis patients, is thought to stimulate the production of immune cells that destroy the amyloid-beta proteins. In studies of mice affected by cognitive impairment mimicking Alzheimer disease in humans, treatment with GM-CSF reduced the burden of amyloid…
- granulocytic leukemia (pathology)
blood disease: Leukemia: …two main varieties of leukemia: myelogenous, or granulocytic, and lymphocytic. These terms refer to the types of cell that are involved. Each of these types is further subdivided into acute and chronic categories, referring to the duration of the untreated disease. Before the advent of modern chemotherapy, patients with acute…
- granuloma (pathology)
skin disease: Appearance: …connective tissues), or chronic and granulomatous, as in chronic cutaneous tuberculosis (lupus vulgaris). In the first instance the changes of acute inflammation discussed above are present but there is normally no epidermal change. In the second, the skin is hardened and thickened, and it has a brownish appearance under the…
- granuloma inguinale (pathology)
granuloma inguinale, contagious sexually transmitted disease occurring predominantly in tropical areas and characterized by deep purulent ulcers on or near the genital organs. Encapsulated bacilli called Donovan bodies (Calymmatobacterium granulomatis) occur in smears from the lesions or in biopsy
- granulomatosis and polyangiitis (medical disorder)
granulomatosis and polyangiitis (GPA), uncommon disorder characterized by inflammation and degeneration of small blood vessels, particularly those in the lungs, kidneys, and sinuses. Granulomatosis and polyangiitis (GPA) is a form of vasculitis, a group of conditions characterized by blood vessel
- granulomatous hepatitis (pathology)
digestive system disease: Chronic active hepatitis: Granulomatous hepatitis, a condition in which localized areas of inflammation (granulomas) appear in a portion of the liver lobule, is a type of inflammatory disorder associated with many systemic diseases, including tuberculosis, sarcoidosis, schistosomiasis, and certain drug reactions. Granulomatous hepatitis rarely leads to serious interference…
- granulomatous inflammation (pathology)
skin disease: Appearance: …connective tissues), or chronic and granulomatous, as in chronic cutaneous tuberculosis (lupus vulgaris). In the first instance the changes of acute inflammation discussed above are present but there is normally no epidermal change. In the second, the skin is hardened and thickened, and it has a brownish appearance under the…
- granulomatous thyroiditis (pathology)
granulomatous thyroiditis, inflammatory disease of the thyroid gland, of unknown but presumably viral origin. It may persist from several weeks to a few months but subsides spontaneously. The disease most frequently occurs in women. The thyroid gland becomes enlarged, and most patients complain of
- granulomatous uveitis (pathology)
uveitis: Granulomatous and nongranulomatous uveitis: Uveitis is also classified as granulomatous (persistent eye inflammation with a grainy surface) and nongranulomatous. Granulomatous uveitis is characterized by blurred vision, mild pain, eye tearing, and mild sensitivity to light. Nongranulomatous uveitis is characterized by acute onset, pain, and intense…
- granum (plant anatomy)
chloroplast: Characteristics of chloroplasts: …tight stacks called grana (singular granum). Grana are connected by stromal lamellae, extensions that run from one granum, through the stroma, into a neighbouring granum. The thylakoid membrane envelops a central aqueous region known as the thylakoid lumen. The space between the inner membrane and the thylakoid membrane is filled…
- Granvelle, Antoine Perrenot de (Spanish cardinal)
Antoine Perrenot de Granvelle was a minister of King Philip II of Spain; he played a major role in the early stages of the Netherlands’ revolt against Philip’s rule. Granvelle, educated at Padua and at Leuven (Louvain), was ordained priest and, in 1540, consecrated bishop of Arras. Pope Pius IV
- Granville (British Columbia, Canada)
Vancouver, city, southwestern British Columbia, Canada. It is the major urban centre of western Canada and the focus of one of the country’s most populous metropolitan regions. Vancouver lies between Burrard Inlet (an arm of the Strait of Georgia) to the north and the Fraser River delta to the
- Granville (France)
Granville, seaside resort, market and harbour town, Manche département, Normandy région, western France. It is located south of Cherbourg and west of Paris. The old walled upper town stands on a promontory jutting out above the harbour and the lower town, which has a bathing beach and promenades.