yeast artificial chromosome
biology
Learn about this topic in these articles:
recombinant DNA
- In recombinant DNA: Creating the clone
Yeast artificial chromosomes (YACs) are vectors based on autonomously replicating plasmids of Saccharomyces cerevisiae (baker’s yeast). In yeast (a eukaryotic organism) a YAC behaves like a yeast chromosome and segregates properly into daughter cells. These vectors can carry the largest inserts of all and are…
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work of Szostak
- In Jack W. Szostak
…the first to create a yeast artificial chromosome (1983), which can be used to clone DNA and consists of a vector (or carrier) molecule that contains yeast genes necessary for replication and a DNA segment of interest.
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