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subacute necrotizing encephalopathy
pathology
Also known as: Leigh disease
Learn about this topic in these articles:
nervous system disorders
- In nervous system disease: Deficiency states
Subacute necrotizing encephalopathy, also called Leigh disease, is a lethal disorder of infancy marked by psychomotor delay, myoclonic jerks, paralyses of eye movements, and respiratory disorders. The precise biochemical defect is unknown, but thiamine metabolism dysfunction may be involved. Seizures in early childhood are the…
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