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meta-iodobenzylguanidine
biochemistry
Also known as: MIBG
Learn about this topic in these articles:
therapies for neuroblastoma
- In neuroblastoma: Treatment and development of targeted therapies
A molecule called metaiodobenzylguanidine (MIBG) is selectively internalized by neuroblastoma cells, and when combined with radiolabeled iodine (iodine-131), MIBG can be used to kill tumour cells. Immunotherapy using antibodies that are directed against neuroblastoma cells also have been tested in clinical trials. Other forms of therapy include synthetic…
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