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clotting factor VIII
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clotting factor VIII

biochemistry

Learn about this topic in these articles:

sex-linked inheritance

  • Barr body
    In human genetic disease: Sex-linked inheritance

    …mutation in the gene encoding clotting factor VIII. Because of this mutation, affected males cannot produce functional factor VIII, so that their blood fails to clot properly, leading to significant and potentially life-threatening loss of blood after even minor injuries. Bleeding into joints commonly occurs as well and may be…

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